The objectives are to test the hypothesis that the tissue re-distribution of PCB are linked to the metabolic status of the Arctic charr and that the tissue re-distribution of PCB associated with fasting will decrease the overall performance characeristics of the Arctic charr.
The project are performed as an experimental study in which laboratory fish or wild fish are contaminated with relistic doses of PCB. Effect parameters include enzyme kinetics, metabolism, endocrine processes and immune status/disease resistance.
A number of laboratory methods are used for the analyses, including RIA and ELISA methods for hormone analyses, molecular methods for enzyme induction analyses. Disease resistance experiments with fish pathogens are performed in a certified fish disease laboratory in Tromsø.
Columbia River Research Laboratory, 5501A Cook-Underwood road, Cook, WA 98605 USA Dept. of Biology, University of Waterloo, Ontario, Canada Polar research Institute of Marine Fisheries and Oceanography (PINRO, 6 Knipovich Street, Murmansk, 183763 Russia.
National Science Foundation, USA
1)The P450 enzyme system of the Arctic charr as a biomarker of POP contamination in the Arctic aquatic environment. 2) The influence of body lipid status on PCB toxicokinetics in the anadromous Arctic charr (Salvelinus alpinus)